Hyperbaric oxygen therapy of spinal cord injury
نویسندگان
چکیده
منابع مشابه
Hyperbaric oxygen therapy of spinal cord injury
Spinal cord injury (SCI) is a complex disease process that involves both primary and secondary mechanisms of injury and can leave patients with devastating functional impairment as well as psychological debilitation. While no curative treatment is available for spinal cord injury, current therapeutic approaches focus on reducing the secondary injury that follows SCI. Hyperbaric oxygen (HBO) the...
متن کاملHyperbaric oxygen therapy improves local microenvironment after spinal cord injury
Clinical studies have shown that hyperbaric oxygen therapy improves motor function in patients with spinal cord injury. In the present study, we explored the mechanisms associated with the recovery of neurological function after hyperbaric oxygen therapy in a rat model of spinal cord injury. We established an acute spinal cord injury model using a modification of the free-falling object method,...
متن کاملHyperbaric oxygen treatment of spinal cord injury in rat model
BACKGROUND The purpose of this study was to investigate the therapeutic effects and mechanisms of hyperbaric oxygen (HBO) treatment on rats following spinal cord injury (SCI). METHODS A total of 45 Sprague-Dawley (SD) rats were randomly divided into three groups. Sham-SCI group was surgically exposed but not subjected to the SCI procedure. SCI-control group was administered SCI and treated wi...
متن کاملHyperbaric oxygen therapy combined with Schwann cell transplantation promotes spinal cord injury recovery
Schwann cell transplantation and hyperbaric oxygen therapy each promote recovery from spinal cord injury, but it remains unclear whether their combination improves therapeutic results more than monotherapy. To investigate this, we used Schwann cell transplantation via the tail vein, hyperbaric oxygen therapy, or their combination, in rat models of spinal cord contusion injury. The combined trea...
متن کاملHyperbaric oxygen therapy provides neuroprotection following spinal cord injury in a rat model.
OBJECTIVE To investigate the effect of hyperbaric oxygen therapy (HBOT) on the iNOS mRNA-iNOS-NO signaling pathway and neurofunction protected in a rat spinal cord injury model. METHODS A total of 36 Sprague-Dawley rats were randomly divided into 3 groups: control group (n=12), SCI group (n=12) and SCI + HBOT group (n=12). SCI + HBOT group In the SCI group and SCI + HBOT groups, SCI was perfo...
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ژورنال
عنوان ژورنال: Medical Gas Research
سال: 2017
ISSN: 2045-9912
DOI: 10.4103/2045-9912.208520